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Resibufogenin

CAT: 0931-T4A2458-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T4A2458-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
465-39-4
Target
Others, NF-κB, Akt, GSK-3, PI3K, DNA/RNA Synthesis, CDK
Related Pathways
Others, DNA Damage/DNA Repair, Stem Cells, Cytoskeletal Signaling, Cell Cycle/Checkpoint, NF-κB, PI3K/Akt/mTOR signaling
Purity
0.9917
Bioactivity
1. Resibufogenin (Bufogenin) is a cytotoxic steroid isolated from the Chinese drug ChanSu. 2. Resibufogenin can inhibit rectifier potassium current (I K) and transient potassium current (I A), it has pathological effects on central nervous system. 3. Resibufogenin corrects hypertension in a rat model of human preeclampsia, it not only prevents the advent of hypertension and proteinuria, but also the development of intrauterine growth restriction.4. Resibufogenina's major metabolic pathway in the human liver is CYP3A4 dominantly mediated 5β-hydroxylation .
Smiles
CC12CCC3C(CCC4CC(O)CCC34C)C11OC1CC2c1ccc(=O)oc1
Molecular Formula
C24H32O4
Molecular Weight
384.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
464614-01Resibufogenin
A12023-5Resibufogenin 5mg
A12023-1Resibufogenin 1mg
A12023-50Resibufogenin 50mg
HY-N0815R-01Resibufogenin (Standard)
A12023-100Resibufogenin 100mg
A12023-25Resibufogenin 25mg

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