Paraxanthine

• Target:

  Endogenous Metabolite|||Drug Metabolite

• Related Pathways:

  Metabolism

• Purity:

  0.9999

• Bioactivity:

  Paraxanthine (1,7-dimethylxanthine) is a metabolite of caffeine (sc-202514) which functions as an adenosine receptor ligand and a PARP-1 inhibitor in pulmonary epithelial cells. Studies suggest that Paraxanthine is structurally similar to caffeine and possibly mediates the physiological effects of caffeine. Also Paraxanthine acts as a competitive phosphodiesterase inhibitor, which increases intracellular cAMP, activates PKA, inhibits TNF-? and leukotriene synthesis. In addition, Paraxanthine acts as a Na+/K+ ATPase enzymatic effector.

• Smiles:

  Cn1cnc2[nH]c(=O)n(C)c(=O)c12

• Molecular Formula:

  C7H8N4O2

• Molecular Weight:

  180.16

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  611-59-6