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Idarubicin

CAT: 0931-T4791-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T4791-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
58957-92-9
Target
Others, DNA/RNA Synthesis, Antifungal, Autophagy, c-Myc, Antibiotic, Antibacterial, Topoisomerase
Related Pathways
Others, DNA Damage/DNA Repair, Autophagy, Microbiology/Virology, Cell Cycle/Checkpoint
Bioactivity
Idarubicin, a potent anthracycline antileukemic agent, is orally active in its application. It functions by inhibiting topoisomerase II, thus interfering with DNA replication and RNA transcription. Furthermore, Idarubicin induces DNA damage, inhibits DNA synthesis, and suppresses c-myc expression. It also demonstrates inhibitory effects on the growth of bacteria and yeasts [1] [2] [3] [4] [5].
Smiles
O([C@@H]1C2=C(C(O)=C3C(=C2O)C(=O)C=4C(C3=O)=CC=CC4)C[C@](C(C)=O)(O)C1)[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5
Molecular Formula
C26H27NO9
Molecular Weight
497.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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GTR19188415-01Idarubicin
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I051-5x10MGIdarubicin Hydrochloride
ALX-380-260-M005Idarubicin . hydrochloride
HY-17381-01Idarubicin (hydrochloride)

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