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T863

CAT: 0931-T4681-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T4681-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
701232-20-4
Target
Transferase, Acyltransferase
Related Pathways
Metabolism
Purity
0.9988
Bioactivity
T-863 (DGAT-1 inhibitor) is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-CoA binding site of DGAT1, and inhibits triacylglycerol synthesis in cells. IC50 value: Target: DGAT1 T863 (DGAT-3) causes weight loss, reduction in serum and liver triglycerides, and improved insulin sensitivity in obese mice.
Smiles
CC1(C)Oc2ncnc(N)c2N=C1c1ccc(cc1)[C@H]1CC[C@H](CC(O)=O)CC1
Molecular Formula
C22H26N4O3
Molecular Weight
394.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C