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Metoclopramide

CAT: 0931-T4616-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T4616-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
364-62-5
Target
Dopamine Receptor, 5-HT Receptor
Related Pathways
Neuroscience, GPCR/G Protein
Purity
0.9981
Bioactivity
Metoclopramide (5-Chloro-2-methoxyprocainamide) is a dopamine D2 antagonist which has been used for treatment of a variety of gastrointestinal symptoms over the last thirty years. In various countries, metoclopramide is the antiemetic drug of choice in pregnant women. Findings provide reassurance regarding the safety of metoclopramide for the fetus when the drug is given to women to relieve nausea and vomiting during pregnancy. Evidence also supports its use for gastroparesis (poor stomach emptying) and gastroesophageal reflux disease. It appears to bind to dopamine D2 receptors where it is a receptor antagonist, and is also a mixed 5-HT3 receptor antagonist/ 5-HT4 receptor agonist.
Smiles
CCN(CC)CCNC(=O)C1=CC(Cl)=C(N)C=C1OC
Molecular Formula
C14H22ClN3O2
Molecular Weight
299.8
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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