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YHO-13177

CAT: 0931-T4595-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T4595-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
912287-56-0
Target
BCRP
Related Pathways
Membrane transporter/Ion channel
Purity
0.9878
Bioactivity
YHO-13177 is a potent and specific inhibitor of BCRP, which enhances the cytotoxicity of SN-38 in cancer cells without affecting P-glycoprotein–mediated paclitaxel resistance in [MDR1]-transduced human leukemia [K562] cells.
Smiles
COc1ccc(cc1OC)C(=C\c1ccc(s1)N1CCC(O)CC1)\C#N
Molecular Formula
C20H22N2O3S
Molecular Weight
370.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C