Ethacrynic acid

• Target:

  NF-?B|||Calcium Channel|||Wnt/beta-catenin|||GST|||NO Synthase

• Related Pathways:

  Membrane transporter/Ion channel|||Cytoskeletal Signaling|||Immunology/Inflammation|||Metabolism|||Oxidation-Reduction|||NF-?B|||Stem Cells

• Purity:

  >99.99%

• Bioactivity:

  Ethacrynic acid (Edecrin) is a nonsulfonamide loop diuretic that inhibits the activity of the Na+/K+/2Cl- cotransporter NKCC2 in the thick ascending limb of the loop of Henle. It also inhibits glutathione S-transferase and Wnt signalling, producing cytotoxicity in chronic lymphocytic leukaemia cells and other tumour cells.

• Smiles:

  CCC(=C)C(=O)C1=CC=C(OCC(O)=O)C(Cl)=C1Cl

• Molecular Formula:

  C13H12Cl2O4

• Molecular Weight:

  303.14

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  58-54-8