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Ethacrynic acid

CAT: 0931-T4564-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T4564-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
58-54-8
Target
NF-κB, Calcium Channel, Wnt/beta-catenin, GST, NO Synthase
Related Pathways
Membrane transporter/Ion channel, Cytoskeletal Signaling, Immunology/Inflammation, Metabolism, Oxidation-Reduction, NF-κB, Stem Cells
Purity
>99.99%
Bioactivity
Ethacrynic acid (Edecrin) is a nonsulfonamide loop diuretic that inhibits the activity of the Na+/K+/2Cl- cotransporter NKCC2 in the thick ascending limb of the loop of Henle. It also inhibits glutathione S-transferase and Wnt signalling, producing cytotoxicity in chronic lymphocytic leukaemia cells and other tumour cells.
Smiles
CCC(=C)C(=O)C1=CC=C(OCC(O)=O)C(Cl)=C1Cl
Molecular Formula
C13H12Cl2O4
Molecular Weight
303.14
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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