Lazertinib

• Target:

  EGFR

• Related Pathways:

  Angiogenesis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors

• Purity:

  0.9996

• Bioactivity:

  Lazertinib (GNS-1480) is an effective, highly mutant-selective and irreversible EGFR-TKI with IC50 values of 1.7 nM, 2 nM, 5 nM, 20.6 nM and 76 nM for Del19/T790M, L858R/T790M, Del19, L85R and Wild type EGFR respectively.

• Smiles:

  COc1cc(N2CCOCC2)c(NC(=O)C=C)cc1Nc1nccc(n1)-n1cc(CN(C)C)c(n1)-c1ccccc1

• Molecular Formula:

  C30H34N8O3

• Molecular Weight:

  554.64

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1903008-80-9