JK-P3

CAT: 0931-T4425-01Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No

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CAT#:0931-T4425-01Size:1 mL - 10 mM (in DMSO)

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

942655-44-9

Target

FGFR, VEGFR

Related Pathways

Tyrosine Kinase/Adaptors, Angiogenesis

Purity

>99.99%

Bioactivity

JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM) . JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube formation in HUVEC without effecting endothelial cell proliferation.

Smiles

COc1ccc(cc1OC)C(=O)Nc1cc([nH]n1)-c1ccccc1

Molecular Formula

C18H17N3O3

Molecular Weight

323.35

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Alternative Products

Catalog	Name
581057	JK-P3
MBS131514	JK184 (JK-184; JK 184)
1726-1	JK 184
MBS5777365	JK-122
ABL-TC0341	Ki-JK
M12911	JK-273

JK-P3

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