JK-P3

• Target :

  FGFR|||VEGFR

• Related Pathways :

  Tyrosine Kinase/Adaptors|||Angiogenesis

• Purity :

  >99.99%

• Bioactivity :

  JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 ?M) . JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube formation in HUVEC without effecting endothelial cell proliferation.

• Smiles :

  COc1ccc(cc1OC)C(=O)Nc1cc([nH]n1)-c1ccccc1

• Molecular Formula :

  C18H17N3O3

• Molecular Weight :

  323.35

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  942655-44-9