JK-P3

• Target:

  FGFR|||VEGFR

• Related Pathways:

  Tyrosine Kinase/Adaptors|||Angiogenesis

• Purity:

  >99.99%

• Bioactivity:

  JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 ?M) . JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube formation in HUVEC without effecting endothelial cell proliferation.

• Smiles:

  COc1ccc(cc1OC)C(=O)Nc1cc([nH]n1)-c1ccccc1

• Molecular Formula:

  C18H17N3O3

• Molecular Weight:

  323.35

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  942655-44-9