Products for Research Use Only

LX2343

CAT: 0931-T4398-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T4398-01Size:2 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
333745-53-2
Target
Beta-Secretase, Beta Amyloid, BACE, Autophagy, PI3K
Related Pathways
Neuroscience, Autophagy, PI3K/Akt/mTOR signaling
Purity
0.9992
Bioactivity
LX2343 is a BACE1 enzyme inhibitor with an IC50 value of 11.43±0.36 μM and acts as a non-ATP competitive PI3K inhibitor with an IC50 of 15.99±3.23 μM. Additionally, LX2343 stimulates autophagy, promoting Aβ clearance.
Smiles
COc1ccc(Cl)cc1N(CC(=O)Nc1ccc2OCOc2c1)S(=O)(=O)c1ccccc1
Molecular Formula
C22H19ClN2O6S
Molecular Weight
474.91
Shipping Conditions
Ice Packs
Storage Temperature
-20°C