PF-4840154

• Target:

  TRP/TRPV Channel

• Related Pathways:

  Membrane transporter/Ion channel

• Purity:

  >99.99%

• Bioactivity:

  PF-4840154 is a potent, selective agonist of the rat and human TrpA1 channel, eliciting TrpA1-mediated nocifensive behavior in mouse, with EC50 values of 97 nM and 23 nM for [rTrpA1] and [hTrpA1], respectively.

• Smiles:

  CC (C) CNc1nc (ncc1C (=O) NCc1ccccc1) N1CCN (CC2CCCOC2) CC1

• Molecular Formula:

  C26H38N6O2

• Molecular Weight:

  466.62

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1332708-14-1