E6446

• Target :

  TLR|||Stearoyl-CoA Desaturase (SCD)

• Related Pathways :

  Immunology/Inflammation|||Metabolism

• Purity :

  0.9999

• Bioactivity :

  E6446 inhibits Toll-like receptor (TLR) 7 and 9 signaling. E6446 works in a variety of human and mouse cell types and inhibits DNA-TLR9 interaction in vitro. When administered to mice, this compound suppress responses to challenge doses of cytidine-phosphate-guanidine (CpG) -containing DNA, which stimulates TLR9.

• Smiles :

  O(CCCN1CCCC1)C=2C=C3C(N=C(O3)C4=CC=C(OCCCN5CCCC5)C=C4)=CC2

• Molecular Formula :

  C27H35N3O3

• Molecular Weight :

  449.59

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1219925-73-1