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Obatoclax

CAT: 0931-T41278-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T41278-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
803712-67-6
Target
Parasite, Autophagy, Bcl-2 Family, Others
Related Pathways
Microbiology/Virology, Autophagy, Others, Apoptosis
Purity
0.9944
Bioactivity
Obatoclax (GX15-070), a pan-BCL-2 family proteins inhibitor and BH3 mimetic, exhibits a binding affinity (K_i) of 220 nM for BCL-2. It promotes autophagy-dependent cell death and cyclin D1 degradation via the proteasome. Additionally, Obatoclax demonstrates anti-cancer properties and broad-spectrum antiparasitic activity.
Smiles
C(=C1N=C(C=C1OC)C2=CC=3C(N2)=CC=CC3)C4=C(C)C=C(C)N4
Molecular Formula
C20H19N3O
Molecular Weight
317.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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