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Thiocolchicine

CAT: 0931-T41248-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T41248-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2730-71-4
Target
Apoptosis, Microtubule Associated
Related Pathways
Cytoskeletal Signaling, Apoptosis
Purity
0.9819
Bioactivity
Thiocolchicine is an effective inhibitor of tubulin polymerization with an IC50 of 2.5 μM and a Ki of 0.7 μM. Thiocolchicine induces cell apoptosis. Thiocolchicine can be used as an ADC cytotoxin in ADC technology.
Smiles
COc1cc2CC[C@H](NC(C)=O)c3cc(=O)c(SC)ccc3-c2c(OC)c1OC
Molecular Formula
C22H25NO5S
Molecular Weight
415.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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AR-C03430-01Thiocolchicine-d3

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