Auraptene

• Target :

  PPAR|||MMP|||BACE|||Antibacterial

• Related Pathways :

  DNA Damage/DNA Repair|||Microbiology/Virology|||Metabolism|||Proteases/Proteasome|||Neuroscience

• Purity :

  >99.99%

• Bioactivity :

  Auraptene is a coumarin derived from citrus plants that bears a geranyloxyl moiety at its C-7. It has anti-inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective activities. It inhibits leukocyte activation and induces phase II enzymes during the initiation phase of carcinogenesis.1 When examined for its potential use in Alzheimer's disease treatment, auraptene was shown to inhibit ?-secretase (BACE1) activity with an IC50 value of 345.1 ?M.

• Smiles :

  CC(C)=CCCC(C)=CCOc1ccc2ccc(=O)oc2c1

• Molecular Formula :

  C19H22O3

• Molecular Weight :

  298.38

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  495-02-3