NCGC00029283

• CAS Number :

  714240-31-0

• Target :

  DNA/RNA Synthesis

• Related Pathways :

  Cell Cycle/Checkpoint|||DNA Damage/DNA Repair

• Purity :

  0.9984

• Bioactivity :

  NCGC00029283 is a potent inhibitor of Werner syndrome helicase-nuclease (WRN), displaying inhibitory activity against WRN helicase with an IC 50 value of 2.3 ?M. Additionally, it exhibits inhibitory effects on Bloom syndrome protein helicase (BLM) and Fanconi anemia group J protein helicase (FANCJ) with IC 50 values of 12.5 ?M and 3.4 ?M, respectively.

• Smiles :

  COc1ccc2[nH]c(=O)c(cc2c1)-c1noc(n1)-c1ccc(F)cc1

• Molecular Formula :

  C18H12FN3O3

• Molecular Weight :

  337.3

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C