Thiophene-2

• Target :

  Others|||Antibacterial

• Related Pathways :

  Microbiology/Virology|||Others

• Bioactivity :

  Thiophene-2 (TP2) is a targeted inhibitor of polyketide synthase 13 (Pks13), specifically designed to disrupt mycolic acid biosynthesis, effectively inducing rapid cell death in mycobacteria. It demonstrates notable anti-tuberculosis activity and exhibits a minimum inhibitory concentration (MIC) value of 1 ?M against Mycobacterium tuberculosis.

• Smiles :

  O=C(OC)C1=C(SC2=C1CCCCC2)NC(=O)C=3C(F)=C(F)C(F)=C(F)C3F

• Molecular Formula :

  C18H14F5NO3S

• Molecular Weight :

  419.37

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  420089-51-6