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8-Aminoadenosine

CAT: 0931-T40483Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T40483Size:2 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3868-33-5
Target
DNA/RNA Synthesis, Others, Akt, Apoptosis, Autophagy, mTOR
Related Pathways
DNA Damage/DNA Repair, PI3K/Akt/mTOR signaling, Others, Autophagy, Apoptosis, Cell Cycle/Checkpoint, Cytoskeletal Signaling
Bioactivity
8-Aminoadenosine (8-NH2-Ado) is an RNA-directed nucleoside analogue that effectively diminishes cellular ATP levels and impedes mRNA synthesis. It also obstructs Akt/mTOR signaling, inducing autophagy and apoptosis in a p53-independent manner. Its significant antitumor activity underscores its therapeutic potential.
Smiles
NC=1N(C=2C(N1)=C(N)N=CN2)[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O
Molecular Formula
C10H14N6O4
Molecular Weight
282.26
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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