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Bisantrene

CAT: 0931-T4047-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T4047-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
78186-34-2
Target
Topoisomerase
Related Pathways
DNA Damage/DNA Repair
Purity
0.9857
Bioactivity
Bisantrene (CL216942) is an anthracenyl bishydrazone with antineoplastic activity. Bisantrene intercalates with and disrupts the configuration of DNA, resulting in DNA single-strand breaks, DNA-protein crosslinking, and inhibition of DNA replication. This agent is similar to doxorubicin in activity, but unlike doxorubicin, does not exhibit cardiotoxicity.
Smiles
C1CN=C(N\N=C\c2c3ccccc3c(\C=N\NC3=NCCN3)c3ccccc23)N1
Molecular Formula
C22H22N8
Molecular Weight
398.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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