T-2513

• CAS Number :

  288247-87-0

• Target :

  Others|||DNA/RNA Synthesis|||Topoisomerase

• Related Pathways :

  DNA Damage/DNA Repair|||Cell Cycle/Checkpoint|||Others

• Bioactivity :

  T-2513 is a potent and specific inhibitor of topoisomerase I. It acts by forming covalent bonds with the topoisomerase I-DNA complex, thereby enhancing its stability. This interaction disrupts the normal process of DNA replication and RNA synthesis, ultimately resulting in cellular apoptosis.

• Smiles :

  CCc1c2Cn3c(cc4c(COC(=O)[C@]4(O)CC)c3=O)-c2nc2ccc(OCCCN)cc12

• Molecular Formula :

  C25H27N3O5

• Molecular Weight :

  449.507

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C