ART812

CAT: 0931-T40236-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T40236-01Size:1 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2607138-82-7

Target

DNA/RNA Synthesis

Related Pathways

Cell Cycle/Checkpoint, DNA Damage/DNA Repair

Purity

0.9932

Bioactivity

ART812 is an orally active inhibitor of DNA polymerase Polθ, possessing an IC50 value of 7.6 nM. Additionally, ART812 exhibits a cell-based microhomology-mediated end joining (MMEJ) IC50 value of 240 nM.

Smiles

CN(C(=O)[C@@H]1[C@H](O)[C@H](O)C(=O)N1c1cc(cc(C)n1)C(F)(F)F)c1ccc(F)c(Cl)c1

Molecular Formula

C19H16ClF4N3O4

Molecular Weight

461.79

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Catalog	Name
GTR19188588-01	ART812

ART812

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