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QS11

CAT: 0931-T4022-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T4022-01Size:2 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
944328-88-5
Target
GTPase, Others, Wnt/beta-catenin
Related Pathways
Stem Cells, Cytoskeletal Signaling, GPCR/G Protein, Others
Purity
>99.99%
Bioactivity
QS11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor. Modulates ARF-GTP levels and synergizes with the Wnt/β-catenin signaling pathway to upregulate β-catenin nuclear translocation. Also reduces in vitro migration of metastatic human breast cancer cells.
Smiles
OC[C@H](Cc1ccccc1)Nc1nc(Oc2ccc3CCCc3c2)nc2n(Cc3ccc(cc3)-c3ccccc3)cnc12
Molecular Formula
C36H33N5O2
Molecular Weight
567.68
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

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C03304-25mgQS11
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Q0685QS11 (QS 11, QS-11, (2S) -2-[2- (Indan-5-yloxy) -9- (1,1'-biphenyl-4-yl) methyl) -9Hpurin-6-ylamino]-3-phenyl-propan-1-ol) discontinued

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