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PD0325901-O-C2-dioxolane

CAT: 0931-T40217Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T40217Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2581116-22-3
Target
Ligands for Target Protein for PROTAC, MEK
Related Pathways
PROTAC, MAPK
Bioactivity
The main body of PD0325901-O-C2-dioxolane is PD0325901, which is a typical non-ATP-competitive MEK1/2 (mitogen-activated protein kinase) inhibitor occupying a variant-binding pocket near the ATP-binding site, with anticancer effects of decreasing ERK phosphorylation and inhibiting cell proliferation.
Smiles
O=C(NOCCC1OCCO1)C2=CC=C(F)C(F)=C2NC3=CC=C(I)C=C3F
Molecular Formula
C18H16F3IN2O4
Molecular Weight
508.23
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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