SGC2085 HCl

CAT: 0931-T4013-01Size: 1 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0931-T4013-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1821908-49-9

Target

Histone Methyltransferase

Related Pathways

Chromatin/Epigenetic

Purity

0.9991

Bioactivity

SGC2085 is a potent and selective coactivator associated arginine methyltransferase 1 (CARM1) Inhibitor with an IC50 of 50 nM and more than undred-fold selectivity over other PRMTs. CARM1 is an important positive modulator of Wnt/β-catenin transcription and neoplastic transformation in colorectal cancer as well as a critical factor in estrogen-stimulated breast cancer growth, and its depletion results in decreased proliferation of myeloid leukemia cells in vivo.

Smiles

C(=O)([C@H](C)N)NCc1cc(c(cc1)Oc1cc(cc(c1)C)C)C.Cl

Molecular Formula

C19H24N2O2·HCl

Molecular Weight

348.87

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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SGC2085 HCl

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