Methyl eugenol

CAT: 0931-MF-0012049-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0012049-01Size:100 mg
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CAS Number
93-15-2
Target
GABA Receptor|||Autophagy|||mTOR|||Akt|||PI3K
Related Pathways
Autophagy|||Membrane transporter/Ion channel|||Cytoskeletal Signaling|||Neuroscience|||PI3K/Akt/mTOR signaling
Purity
0.9816
Bioactivity
1. Methyl eugenol (4-allylveratrole) is a natural constituent of the essential oils of a number of plants widely used in foodstuffs as flavouring agents, in view of the carcinogenic potential of ME, the need to check its presence in food products with effective analytical methods. 2. Methyleugenol has insecticidal properties. 3. Methyleugenol can inhibit the production of nitric oxide and decreased the protein expression of inducible nitric oxide synthase, it down-regulates the production of pro-inflammatory cytokines in the ischemic brain as well as in immunostimulated mixed glial cells; indicates that methyleugenol could be useful for the treatment of ischemia/inflammation-related diseases. 4. Methyleugenol has cytotoxicity and genotoxicity. 5. Intravenous (i.v.) treatment with methyleugenol (ME) in either anesthetized or conscious rats elicits hypotension, an effect that seems related to an active vascular relaxation rather than withdrawal of sympathetic tone. 6. Methyleugenol has antinociceptive effect on the second phase of formalin-induced pain, may be due to the inhibition of N-methyl-d-aspartic acid (NMDA) receptor-mediated hyperalgesia via GABA (A) receptors. 7. Methyleugenol has elaxant and antispasmodic actions on guinea-pig isolated ileum.
Smiles
O(C)C1=C(OC)C=CC(CC=C)=C1
Molecular Formula
C11H14O2
Molecular Weight
178.23
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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