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Aristolactam I

CAT: 0931-T3S1227-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T3S1227-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
13395-02-3
Target
Drug Metabolite, Cadherin, Aquaporin, Caspase, Apoptosis, TGF-beta/Smad
Related Pathways
Membrane transporter/Ion channel, Stem Cells, Apoptosis, Cytoskeletal Signaling, Metabolism, Proteases/Proteasome
Purity
0.9963
Bioactivity
1.Aristolactam I (Aristololactum) has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway. 2. The effects of Aristololactam I may be mediated by different mechanisms except TGF-beta1 pathway. 3. Aristololactam I may be one of toxic metabolites in Chinese herbs containing AA which participate in renal damage and fibrosis.
Smiles
COc1cccc2c1cc1NC(=O)c3cc4OCOc4c2c13
Molecular Formula
C17H11NO4
Molecular Weight
293.27
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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