AU-15330

• Target:

  PROTACs|||Epigenetic Reader Domain

• Related Pathways:

  PROTAC|||Chromatin/Epigenetic

• Purity:

  >99.99%

• Bioactivity:

  AU-15330 is a proteolytic targeting chimera (PROTAC) that simultaneously targets SMARCA4, SMARCA2, and PBRM1 for degradation and exhibits cytotoxicity in H3.3K27M cells but not in H3 wild-type cells. [2]

• Smiles:

  C[C@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](NC(=O)CN1CCN(CC1)c1cc(nnc1N)-c1ccccc1O)C(C)(C)C)c1ccc(cc1)-c1scnc1C

• Molecular Formula:

  C39H49N9O5S

• Molecular Weight:

  755.93

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2380274-50-8