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WSF1-IN-1

CAT: 0931-T39947-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T39947-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2379577-82-7
Target
Transmembrane Glycoprotein
Related Pathways
Neuroscience
Purity
0.999
Bioactivity
WSF1-IN-1 is an orally bioavailable small-molecule inhibitor of the WSF1 protein, designed for the investigation of WSF1-associated tumorigenesis in Wolfram syndrome. in studies using HepG2 parental and HepG2 WFS1 knockout cell lines, WSF1-IN-1 demonstrated differential inhibitory potency with IC50 values of 0.33 μM, confirming its target selectivity and mechanistic specificity in modulating WSF1-related cellular pathways.
Smiles
CN1C=2C(=C(C)N=C(NCC3=CN(CC=4C=CC(C(F)(F)F)=NC4)N=C3)N2)NC(=O)[C@@H]1C
Molecular Formula
C20H21F3N8O
Molecular Weight
446.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C