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HSD1590

CAT: 0931-T39944-01Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0931-T39944-01Size:1 mL - 10 mM (in DMSO)
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2379279-96-4
Target
Others, ROCK
Related Pathways
Stem Cells, Others, Cell Cycle/Checkpoint, Cytoskeletal Signaling
Bioactivity
HSD1590 is a highly effective and potent inhibitor of ROCK1 and ROCK2, with IC50 values of 1.22 nM and 0.51 nM, respectively. It demonstrates exceptional binding affinity to ROCK, with Kd values below 2 nM. Moreover, HSD1590 showcases minimal cytotoxicity, making it an ideal compound for various applications.
Smiles
COc1c(cccc1-c1nc2ccc3[nH]ncc3c2c2CCCc12)B(O)O
Molecular Formula
C20H18BN3O3
Molecular Weight
359.19
Shipping Conditions
Ice Packs
Storage Temperature
-20°C