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DGN549-C

CAT: 0931-T39458Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T39458Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2058075-34-4
Target
Drug-Linker Conjugates for ADC
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
DGN549-C is a novel compound featuring a cleavable ADC (antibody-drug conjugate) linker composed of valine-alanine (va) and a PBD (pyrrolobenzodiazepine) dimer. This compound possesses a unique DNA-alkylating cytotoxic payload, DGN549, which is utilized in the development of ADCs.
Smiles
[H][C@@]12Cc3ccccc3N1C(=O)c1cc(OC)c(OCc3cc(COc4cc5N=C[C@]6([H])Cc7ccccc7N6C(=O)c5cc4OC)cc(NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)CCCCC(=O)NCCN4C(=O)C=CC4=O)c3)cc1NC2 |c:30,80|
Molecular Formula
C60H61N9O12
Molecular Weight
1100.199
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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