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Dapolsertib

CAT: 0931-T39085-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T39085-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1616359-00-2
Target
Pim, FLT, Apoptosis
Related Pathways
Tyrosine Kinase/Adaptors, JAK/STAT signaling, Apoptosis, Angiogenesis, Chromatin/Epigenetic
Purity
0.9961
Bioactivity
Dapolsertib (SEL24-B489) is an orally bioavailable and potent PIM and FLT3-ITD inhibitor, inhibiting PIM1, PIM2, and PIM3, decreasing PIM substrate phosphorylation, and inducing dose-dependent apoptosis in leukemia cells.
Smiles
O=N(=O)C=1C(Br)=C(Br)C=C2C1N=C(N2C(C)C)C3CCNCC3
Molecular Formula
C15H18Br2N4O2
Molecular Weight
446.14
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
BUP21064-01Dapolsertib

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