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Simotinib hydrochloride

CAT: 0931-T39019Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T39019Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1538617-88-7
Target
Others, EGFR
Related Pathways
Others, Angiogenesis, JAK/STAT signaling, Tyrosine Kinase/Adaptors
Bioactivity
Simotinib hydrochloride is a selective and orally bioavailable EGFR tyrosine kinase inhibitor, showing strong specificity with an IC 50 of 19.9 nM. This compound exhibits potent antineoplastic activities.
Smiles
Cl.COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCN1CC2(CC2)C2(C1)OCCO2
Molecular Formula
C25H27Cl2FN4O4
Molecular Weight
537.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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