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Platycodin D

CAT: 0931-T3889-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T3889-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
58479-68-8
Target
AMPK, Prostaglandin Receptor, Wnt/beta-catenin
Related Pathways
Stem Cells, Cytoskeletal Signaling, GPCR/G Protein, Chromatin/Epigenetic, Immunology/Inflammation, PI3K/Akt/mTOR signaling
Purity
0.9979
Bioactivity
Platycodin D may stimulate TNF-α synthesis or inhibit degradation of TNF-α mRNA. Platycodin D (10/30 μM) suppresses prostaglandin E2 production in rat peritoneal macrophages stimulated by the protein kinase C activator 12-O-tetradecanoyl phorbol 13-acetate (TPA) . Platycodin D and D3 are useful as expectorant agents in the treatment of various airway diseases, they can increase mucin release from rat and hamster tracheal surface epithelial cell culture and also from intact rat trachea upon nebulization.
Smiles
C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@@H](O)CO[C@H]2OC(=O)[C@]23CCC(C)(C)C[C@H]2C2=CC[C@@H]4[C@@]5(C)C[C@H](O)[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)C(CO)(CO)[C@@H]5CC[C@@]4(C)[C@]2(C)C[C@H]3O)[C@H](O)[C@H](O)[C@H]1O[C@@H]1OC[C@@H](O)[C@H](O[C@@H]2OC[C@](O)(CO)[C@H]2O)[C@H]1O
Molecular Formula
C57H92O28
Molecular Weight
1225.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C