Platycodin D

• Target:

  AMPK|||Prostaglandin Receptor|||Wnt/beta-catenin

• Related Pathways:

  Stem Cells|||Cytoskeletal Signaling|||GPCR/G Protein|||Chromatin/Epigenetic|||Immunology/Inflammation|||PI3K/Akt/mTOR signaling

• Purity:

  0.9979

• Bioactivity:

  Platycodin D may stimulate TNF-? synthesis or inhibit degradation of TNF-? mRNA. Platycodin D (10/30 ?M) suppresses prostaglandin E2 production in rat peritoneal macrophages stimulated by the protein kinase C activator 12-O-tetradecanoyl phorbol 13-acetate (TPA) . Platycodin D and D3 are useful as expectorant agents in the treatment of various airway diseases, they can increase mucin release from rat and hamster tracheal surface epithelial cell culture and also from intact rat trachea upon nebulization.

• Smiles:

  C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@@H](O)CO[C@H]2OC(=O)[C@]23CCC(C)(C)C[C@H]2C2=CC[C@@H]4[C@@]5(C)C[C@H](O)[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)C(CO)(CO)[C@@H]5CC[C@@]4(C)[C@]2(C)C[C@H]3O)[C@H](O)[C@H](O)[C@H]1O[C@@H]1OC[C@@H](O)[C@H](O[C@@H]2OC[C@](O)(CO)[C@H]2O)[C@H]1O

• Molecular Formula:

  C57H92O28

• Molecular Weight:

  1225.32

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  58479-68-8