Esculentoside A

• Target :

  COX|||NF-?B

• Related Pathways :

  NF-?B|||Neuroscience|||Immunology/Inflammation

• Purity :

  0.9985

• Bioactivity :

  Esculentoside A can suppress inflammatory responses in LPS-induced ALI through inhibition of the NF-?B and mitogen-activated protein kinase signaling pathways. Esculentoside A may be useful for the treatment of autoimmune disease through modulation on T cell-mediated adaptive immunity. Esculentoside A may play significant roles in the treatment of BXSB mice through modulation of inflammatory cytokines, inhibition of renal cell proliferation and induction of apoptosis.

• Smiles :

  COC(=O)[C@@]1(C)CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@H](O)[C@H](O[C@@H]6OC[C@@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)[C@@](C)(CO)[C@@H]5CC[C@@]34C)[C@@H]2C1)C(O)=O

• Molecular Formula :

  C42H66O16

• Molecular Weight :

  826.96

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  65497-07-6