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SAR247799

CAT: 0931-T38716Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T38716Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1315311-14-8
Target
LPL Receptor, S1P Receptor
Related Pathways
GPCR/G Protein
Bioactivity
SAR247799 (S1P1 agonist 3) is a selective and G-protein-biased S1P1 agonist that activates downstream G-protein signaling pathways more preferentially than β-blocker proteins and internalized signaling pathways, activates S1P 1 on endothelial cells without causing receptor desensitization, and protects the endothelium without affecting lymphocyte populations, and can be used to study type 2 diabetes, endothelial dysfunction and vascular hyperpermeability.
Smiles
O=C(O)COC=1C(=CC(=CC1C)C2=NC3=CN=C(N=C3O2)OC=4C=CC=C(Cl)C4)C
Molecular Formula
C21H16ClN3O5
Molecular Weight
425.82
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
MBS5799316-01SAR247799

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