Agnuside

CAT: 0931-T3868-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T3868-01Size:1 mg
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CAS Number
11027-63-7
Target
P-gp|||Caspase|||HIF/HIF Prolyl-Hydroxylase|||ASCT|||COX|||Prostaglandin Receptor|||NO Synthase
Related Pathways
Chromatin/Epigenetic|||Proteases/Proteasome|||Apoptosis|||Neuroscience|||Membrane transporter/Ion channel|||Immunology/Inflammation|||GPCR/G Protein|||Metabolism
Purity
0.9981
Bioactivity
Agnuside (chasteberry oil) inhibits COX-2 (IC50: 0.026 mg/ml) but exhibits less than 10% inhibition of COX-1 at this concentration. It also inhibits 46.3, 66.8, and 82.1% of P-glycoprotein (P-gp) ATPase activity at concentrations of 5, 25, and 100 ?M, respectively.
Smiles
OC[C@H]1O[C@@H](O[C@@H]2OC=C[C@H]3[C@H](O)C=C(COC(=O)c4ccc(O)cc4)[C@@H]23)[C@H](O)[C@@H](O)[C@@H]1O
Molecular Formula
C22H26O11
Molecular Weight
466.44
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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