AP 811

• Target :

  Natriuretic peptide

• Related Pathways :

  GPCR/G Protein

• Bioactivity :

  AP 811, a selective antagonist of the atrial natriuretic peptide clearance receptor (APN-CR, NPR3) with a K i value of 0.48 nM, exhibits remarkable selectivity for NPR3 over NPR1 by more than 20,000-fold. Moreover, AP 811 effectively eliminates ANP-induced pump stimulation.

• Smiles :

  CCC(C)CNC(=O)C(CCCNC(N)=N)NC(=O)C(CC(O)=O)NC(=O)C(NC(=O)C(CCCNC(N)=N)NC(=O)Cc1ccc(NC(=O)c2ccc3ccccc3c2)cc1)C(C)CC

• Molecular Formula :

  C46H66N12O8

• Molecular Weight :

  915.11

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  124833-45-0