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Irigenin

CAT: 0931-T3862-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T3862-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
548-76-5
Target
Integrin, Apoptosis, NF-κB
Related Pathways
NF-κB, Cytoskeletal Signaling, Apoptosis
Purity
0.9985
Bioactivity
Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra Domain A domain. It can sensitize TRAIL-induced apoptosis by enhancing the expression of pro-apoptotic molecules in gastric cancer cells and has anti-cancer effects.
Smiles
COc1cc(cc(O)c1OC)-c1coc2cc(O)c(OC)c(O)c2c1=O
Molecular Formula
C18H16O8
Molecular Weight
360.31
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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