NSC 80467

• CAS Number :

  101982-51-8

• Target :

  Survivin

• Related Pathways :

  Apoptosis

• Purity :

  0.9925

• Bioactivity :

  NSC 80467 is a selective DNA-damaging agent that functions through survivin inhibition. NSC 80467 preferentially disrupts DNA synthesis, thereby inducing two hallmark DNA-damage markers, ?H2AX and pKAP1. NSC 80467 enables mechanistic investigation in to DNA replication stress and apoptosis-associated signaling pathways and serves as a biochemical tool for evaluating survivin-dependent cellular processes in oncology research.

• Smiles :

  O=C1C2=C(C(C3=C1N(CC(C)C)C(C)=[N+]3CC(C4=CC=C([N+]([O-])=O)C=C4)=O)=O)C=CC=C2.[Br-]

• Molecular Formula :

  C24H22BrN3O5

• Molecular Weight :

  512.35

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C