Lipoxin B4 methyl ester

• Target:

  Others|||Leukotriene Receptor

• Related Pathways:

  GPCR/G Protein|||Others

• Bioactivity:

  Lipoxin B4 (LXB4) methyl ester is a lipid-soluble prodrug form of the transcellular metabolite LXB4, which is a positional isomer of LXA4 produced by the metabolism of 15-HETE or 15-HpETE by human leukocytes. At 100 nM, LXB4 inhibits polymorphonuclear leukocyte (PMN) migration stimulated by leukotriene B4 and inhibits LTB4-induced adhesion of PMNs with an IC50 of 0.3 nM.

• Smiles:

  CCCCC[C@H] (O) [C@H] (O) \C=C\C=C\C=C/C=C/[C@@H] (O) CCCC (=O) OC

• Molecular Formula:

  C21H34O5

• Molecular Weight:

  366.498

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  97589-07-6