Products for Research Use Only
RegisterLogin

4-CPPC

CAT: 0931-T38293-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T38293-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
29553-70-6
Target
MIF, Others, CD74
Related Pathways
Immunology/Inflammation, Others
Purity
0.9803
Bioactivity
4-CPPC is an inhibitor of macrophage migration inhibitory factor-2 (MIF-2; IC50= 27 μM) .1It is selective for MIF-2 over MIF-1 (IC50= 450 μM) . It inhibits MIF-2, but not MIF-1, binding to CD74in vitrowhen used at a concentration of 10 μM. 4-CPPC (5, 10, and 25 μM) inhibits MIF-2-induced ERK1/2 phosphorylation in primary human skin fibroblasts.
Smiles
OC(=O)C1=CC=CC(=C1)C1=CC(=NC=C1C(O)=O)C(O)=O
Molecular Formula
C14H9NO6
Molecular Weight
287.22
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

4-(3-carboxyphenyl)pyridine-2,5-dicarboxylic Acid
CAS Number29553-70-6
PubChem CID893698
IUPAC Name4-(3-carboxyphenyl)pyridine-2,5-dicarboxylic acid
Molecular FormulaC14H9NO6
Molecular Weight287.22
XLogP1.4
Topological Polar Surface Area125
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count7
Rotatable Bond Count4
Heavy Atom Count21
Formal Charge0
Complexity437
SMILES
C1=CC(=CC(=C1)C(=O)O)C2=CC(=NC=C2C(=O)O)C(=O)O
InChI
InChI=1S/C14H9NO6/c16-12(17)8-3-1-2-7(4-8)9-5-11(14(20)21)15-6-10(9)13(18)19/h1-6H,(H,16,17)(H,18,19)(H,20,21)
InChIKey
NBVHLJGGHJLTGM-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 4-(3-carboxyphenyl)pyridine-2,5-dicarboxylic Acid
CAS: 29553-70-6
CID: 893698
Formula: C14H9NO6
MW: 287.22
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight287.22
XLogP31.4
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count7
Rotatable Bond Count4
Exact Mass287.04298701
Monoisotopic Mass287.04298701
Topological Polar Surface Area125 Ų
Heavy Atom Count21
Formal Charge0
Complexity437
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
TN11346-014,4'-Diapo-ω, ω-carotene-4,4'-dial
TYD-02042-014- (4-Bromophenyl) -4-hydroxypiperidine
T5943-014,4'-DIMETHOXYBENZIL
TN9540-014,4'-Dimethyldiphenyl
TYD-006474,4'-Dichlorobenzophenone
T13507-014,4'-Iminodiphenol
TYD-03491-014,4'-Trimethylenedipyridine
PDK02004,4-Difluorobenzhydrol
TPL0369-014,4'-Dimethoxybenzophenone
PDK04034,4'-Dihydroxybiphenyl

Alternative Products

CatalogName
BA6080-14-CPPC
BLG-D127-025Cp2C /CppC
MBS1134588-01Recombinant Neisseria gonorrhoeae Cryptic plasmid protein C (cppC)
VAng-Wyb2088-1mgEcoliRecombinant Neisseria Gonorrhoeae cppC Protein (aa 1-205)
MBS256046-01P1, P2- Di- (cytidine- 5')- diphosphate (Cp2C / CppC)
D 127-025P¹, P²- Di- (cytidine- 5') - diphosphate (Cp₂C / CppC), sodium salt
PC64124,4,4-Trifluorobutyl 4,4,4-trifluorobutanoate
PC52154,4,4,4',4',4'-Hexafluorovaline hydrochloride
OR1011238-014,4,4,4-Silanetetrayltetrabenzaldehyde
OR1011273-014,4',4'',4'''-Methanetetrayltetrabenzaldehyde

Popular Products