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MnTBAP chloride

CAT: 0931-T38164Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T38164Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
55266-18-7
Target
Antioxidant, NF-κB
Related Pathways
NF-κB, Oxidation-Reduction
Bioactivity
MnTBAP chloride (Mn (III) TBAP) is a cell-permeable superoxide dismutase (SOD) mimetic and peroxynitrite scavenger that reduces the doubling time of SOD-E. coli by a factor of 2. MnTBAP chloride exhibits anti-inflammatory effects through upregulation of BMPR-II and inhibition of NFκB signaling. mnTBAP chloride is a manganese porphyrin complex with antioxidant properties and has potential for use in the study of fibrotic responses in chronic kidney diseases (CKDs) .
Smiles
[H+].O=C([O-])C=1C=CC(=CC1)C2=C3C=CC=4C(C=5C=CC(=CC5)C(=O)[O-])=C6C=CC7=C(C8=CC=C(C=C8)C(=O)[O-])C=9C=CC%10=C(C%11=CC=C(C=C%11)C(=O)[O-])C%12=CC=C2[N-]%12[Mn+3]([Cl-])([N]34)([N]%109)[N-]67
Molecular Formula
C48H25ClMnN4O8
Molecular Weight
876.13
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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