MnTBAP chloride

• Target:

  Antioxidant|||NF-?B

• Related Pathways:

  NF-?B|||Oxidation-Reduction

• Bioactivity:

  MnTBAP chloride (Mn (III) TBAP) is a cell-permeable superoxide dismutase (SOD) mimetic and peroxynitrite scavenger that reduces the doubling time of SOD-E. coli by a factor of 2. MnTBAP chloride exhibits anti-inflammatory effects through upregulation of BMPR-II and inhibition of NF?B signaling. mnTBAP chloride is a manganese porphyrin complex with antioxidant properties and has potential for use in the study of fibrotic responses in chronic kidney diseases (CKDs) .

• Smiles:

  [H+].O=C ([O-]) C=1C=CC (=CC1) C2=C3C=CC=4C (C=5C=CC (=CC5) C (=O) [O-]) =C6C=CC7=C (C8=CC=C (C=C8) C (=O) [O-]) C=9C=CC%10=C (C%11=CC=C (C=C%11) C (=O) [O-]) C%12=CC=C2[N-]%12[Mn+3] ([Cl-]) ([N]34) ([N]%109) [N-]67

• Molecular Formula:

  C48H25ClMnN4O8

• Molecular Weight:

  876.13

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  55266-18-7