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Aquastatin A

CAT: 0931-T38069Size: 2500 μgDry Ice: NoHazardous: No
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CAT#:0931-T38069Size:2500 μg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
153821-50-2
Target
Others
Related Pathways
Others
Bioactivity
Aquastatin A is a fungal metabolite originally isolated fromF. aquaeductuumthat has diverse biological activities.1It is active againstS. aureus (MIC = 32 μg/ml) and inhibits enoyl-acyl carrier protein reductase (Fabl; IC50= 3.2 μM) andS. aureusfatty acid synthesis (IC50= 3.5 μM) .2Aquastatin A also inhibits the Na+/K+-ATPase and H+/K+-ATPase (IC50s = 7.1 and 6.2 μM, respectively), as well as protein tyrosine phosphatase 1B (PTP1B; IC50= 0.19 μM) .1,3
Smiles
CCCCCCCCCCCCCCCc1cc(O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)cc(O)c1C(=O)Oc1cc(C)c(C(O)=O)c(O)c1
Molecular Formula
C36H52O12
Molecular Weight
676.8
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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