Corilagin

CAT: 0931-MF-0016416-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0016416-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
23094-69-1
Target
Apoptosis|||Autophagy|||Reverse Transcriptase|||TLR|||Antibacterial
Related Pathways
Immunology/Inflammation|||Apoptosis|||Microbiology/Virology|||Autophagy
Purity
0.9999
Bioactivity
Corilagin has anti-inflammatory activity. Corilagin has a significant antitumour potential and lower toxicity in normal cells in vitro.Corilagin can enhance the cytotoxicity of both cisplatin and doxorubicin on the Hep3B hepatoma cells.Corilagin has antiviral activity, reduces the cytotoxicity induced by EV71 or CA16 on Vero cells with and IC50 value of 5.6 and 32.33 ?g/mL, respectively. Corilagin shows the potential to protect against HSV-1-induced encephalitis, and the beneficial effects may be mediated by inhibiting TLR2 signaling pathways.Corilagin has antifibrotics property and is potentiated in treating idiopathic pulmonary fibrosis (IPF), attenuates bleomycin-induced epithelial injury and fibrosis via inactivation of oxidative stress, proinflammatory cytokine release and NF-?B and TGF-?1 signaling. Solvent:Pyridine, Methanol, Ethanol, etc.
Smiles
O[C@H]1[C@H]2COC(=O)c3cc(O)c(O)c(O)c3-c3c(O)c(O)c(O)cc3C(=O)O[C@H]1[C@H](O)[C@H](OC(=O)c1cc(O)c(O)c(O)c1)O2
Molecular Formula
C27H22O18
Molecular Weight
634.45
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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