ASB 14780

CAT: 0931-MF-0044615Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0044615Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1069046-00-9
Target
Others
Related Pathways
Others
Bioactivity
Potent and selective cytosolic phospholipase A2 alpha (cPLA2?) inhibitor (IC50 = 20 nM) . Selective for cPLA2? over secreted PLA2? (sPLA2?; exhibits no inhibition at 10 ?M) . Inhibits cPLA2?-dependent inflammatory responses in vitro in guinea pig and human whole-blood assays. Improves diet-induced liver injury and CCl4-induced hepatic fibrosis in vivo. Orally bioavailable.
Smiles
NC(CO)(CO)CO.OC(=O)CCc1ccc2n(cc(CCc3ccccc3)c2c1)-c1ccc(Oc2ccccc2)cc1
Molecular Formula
C35H38N2O6
Molecular Weight
582.697
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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