5-hydroxy Omeprazole

• Target:

  Drug Metabolite|||Others

• Related Pathways:

  Metabolism|||Others

• Bioactivity:

  5-hydroxy Omeprazole is a major metabolite of omeprazole , an inhibitor of the gastric H+/K+-ATPase pump.[1] 5-hydroxy Omeprazole is produced from omeprazole by the action of cytochrome P450 (CYP) isoform 2C19, a monooxygenase. [2][3] CYP2C19 polymorphisms significantly influence the metabolism of omeprazole, and individuals may be classified as homozygous extensive metabolizers, heterozygous extensive metabolizers, and poor metabolizers.[1]

• Smiles:

  COc1ccc2nc([nH]c2c1)S(=O)Cc1ncc(CO)c(OC)c1C

• Molecular Formula:

  C17H19N3O4S

• Molecular Weight:

  361.42

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  92340-57-3