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Fumaric acid

CAT: 0931-T3763-01Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0931-T3763-01Size:1 mL - 10 mM (in DMSO)
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
110-17-8
Target
Endogenous Metabolite, NF-κB, p38 MAPK
Related Pathways
NF-κB, MAPK, Metabolism
Purity
0.9928
Bioactivity
Fumaric acid (2-Butenedioic acid) attenuates the eotaxin-1 expression in TNF-α-stimulated fibroblasts by suppressing p38 MAPK-dependent NF-κB signaling. Fumaric acid has recently been identified as an oncometabolite or an endogenous, cancer-causing metabolite. High levels of this organic acid can be found in tumors or biofluids surrounding tumors. Its oncogenic action appears due to its ability to inhibit prolyl hydroxylase-containing enzymes.
Smiles
C(=C/C(O)=O)\C(O)=O
Molecular Formula
C4H4O4
Molecular Weight
116.07
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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CatalogName
FF23617-01Fumaric acid

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