Oleyl Anilide

CAT: 0931-MF-0036321-01Size: 50 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0036321-01Size:50 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
5429-85-6
Target
Acyltransferase|||Others
Related Pathways
Metabolism|||Others
Bioactivity
AcylCoA:cholesterol acyltransferase (ACAT) is an intracellular cholesteryl ester synthase tied closely to the absorption of dietary cholesterol. Oleyl analide (OA) is a weak inhibitor of acylCoA:cholesterol acyltransferase (ACAT) with an IC50 of 26 ?M. OA and the related glyceride dioleoyl phenylamino propane 1,2-diol have been linked to a syndrome of eosinophilia, excessive T-cell activation, and elevated interleukin-4 (IL-4), soluble IL-2R, and IL-5. The clinical consequences are an acute pulmonary inflammatory reaction followed by chronic neuropathy, myalgia, and autoimmune connective tissue disease, generally referred to as toxic oil syndrome (TOS) . Aniline-denatured cooking oil is a source of OA associated with TOS.
Smiles
N(C(CCCCCCC/C=C\CCCCCCCC)=O)C1=CC=CC=C1
Molecular Formula
C24H39NO
Molecular Weight
357.57
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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