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(+) -Macrosphelide A

CAT: 0931-T37552Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T37552Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
172923-77-2
Target
Others, Antibiotic
Related Pathways
Microbiology/Virology, Others
Bioactivity
(+) -Macrosphelide A is a fungal metabolite originally isolated from Microsphaeropsis. It inhibits adhesion of HL-60 human leukemia cells to human umbilical vein endothelial cells (HUVECs) in a concentration-dependent manner. It also inhibits the growth of SKOV3 ovarian cancer cells in a concentration-dependent manner. (+) -Macrosphelide A inhibits the growth of Gram-positive bacteria, including B. subtilis, M. luteus, B. thuringiensis, and S. aureus (MICs = 143, 143, 57, and 57 μg/ml, respectively), but not Gram-negative bacteria or fungi.
Smiles
C[C@H]1CC(=O)O[C@@H](C)[C@H](O)\C=C\C(=O)O[C@@H](C)[C@H](O)\C=C\C(=O)O1 |t:10,19|
Molecular Formula
C16H22O8
Molecular Weight
342.344
Shipping Conditions
Ice Packs
Storage Temperature
-20°C