Amycolatopsin A

CAT: 0931-MF-0065748Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0065748Size:5 mg
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CAS Number
2209112-96-7
Target
Antibacterial|||Others
Related Pathways
Others|||Microbiology/Virology
Bioactivity
Amycolatopsin A is a macrolide polyketide originally isolated fromAmycolatopsisthat has antimycobacterial and anticancer activities.1It is active againstM. bovisandM. tuberculosis (IC50s = 0.4 and 4.4 ?M, respectively) but notB. subtilis, S. aureus, E. coli, orP. aeruginosa (IC50s = >30 ?M for all) . Amycolatopsin A is cytotoxic to SW620 colorectal and NCI H460 lung cancer cells (IC50s = 0.08 and 1.2 ?M, respectively) .
Smiles
COCCC[C@H]1O[C@@](O)([C@@H](C)C2CC(OC)C(O)\C=C(\C)/C=C(\C)/C=C(C)/C(O[C@H]3O[C@H](C)[C@@H](OC)[C@H](O)[C@H]3O)C(C)\C=C(/CO)\C=C(/OC)\C=C(C)\C(=O)O2)[C@H](OC)[C@@H](O)[C@]1(C)O[C@H]1C[C@H](O)[C@H](O[C@H]2C[C@@](C)(O)[C@H](O)[C@@H](C)O2)[C@@H](C)O1
Molecular Formula
C60H98O23
Molecular Weight
1187.421
Shipping Conditions
Cool pack
Storage Temperature
-20°C

Alternative Products

CatalogName
A207-5MGAmycolatopsin A
A209-0.5MGAmycolatopsin C
A208-0.5MGAmycolatopsin B

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